<div class="write--template" style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);"> <div class="template-title" style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline;"> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; text-align: center;"><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;"><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; font-size: 24pt;">전기천공법과 CAR-NK세포 결합으로 간암 치료 효과 높여</span></span></p></div> <div class="template-descrition" style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline;"> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; text-align: center;"><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; font-size: 18pt;"><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">- 국소 종양 미세환경 개선과 세포치료 결합한 복합 면역치료법 개발 -</span></span></p></div></div> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);">□ 국내 연구진이 <span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">전기적 소작기법을 이용해 간암에 대한 면역세포 치료의 효과를 증진</span>시키는 새로운 복합 면역치료법을 개발했다.</p> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);"> </p> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);">□ 한국연구재단(이사장 홍원화)은 <span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">성균관대학교 박우람 교수</span> 연구팀이 <span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">비가역적 전기천공법</span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">(IRE)*</span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">을 활용</span>해 간암 병변의 면역억제성 종양 미세환경을 변화시키고, <span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">키메라 항원 수용체</span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">(CAR)** </span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">자연살해세포</span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">(NK)***</span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">의 항암 능력을 증진시키는 결과를 얻었으며</span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">, </span><span style="box-sizing: border-box; border: 0px; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; font-weight: bolder; vertical-align: baseline;">이에 대한 핵심 분자 경로를 규명</span>했다고 밝혔다. 이는 난치성 고형암 치료의 새로운 전략을 제시하는 중요한 성과로 평가된다.</p> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);">* 비가역적 전기천공법(IRE, Irreversible electroporation): 고전압의 전기 펄스를 가해 세포막에 복구 불가능한 구멍을 내어 세포를 사멸시키는 비열 전기소작술</p> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);">** 키메라 항원 수용체 (CAR, Chimeric antigen receptor): 특정 암세포의 특정 항원을 표적할 수 있는 인공으로 제작된 수용체 단백질</p> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);">*** 자연살해세포(NK, Natural killer): 암세포를 선택적으로 살해할 수 있는 선천면역세포로, 암의 발생 및 전이 등을 효과적으로 억제하여 면역세포기반 항암치료제로써 주목받고 있음</p> <p style="box-sizing: border-box; border: 0px; margin-right: 0px; margin-left: 0px; padding: 0px; -webkit-font-smoothing: antialiased; text-rendering: optimizelegibility; text-size-adjust: 100%; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Pretendard, NotoSansRN; font-size: 17px; background-color: rgb(255, 255, 255);"><br></p> <p style="box-sizing: inherit; margin-right: 0px; margin-left: 0px; padding: 0px; list-style: none; text-size-adjust: none; color: rgb(127, 127, 127); font-family: Golfzon, 'Noto Sans Korean', nanumGothic, Dotum, sans-serif; font-size: 14px; letter-spacing: -1px;"><span style="box-sizing: inherit; color: rgb(41, 41, 41); font-family: '맑은 고딕'; font-size: 11pt; letter-spacing: normal;">(계속)</span></p><pre class="b-pre" style="box-sizing: inherit; color: rgb(51, 51, 51); font-size: 1.6rem; margin: 0px; padding: 0px; border: 0px; font-family: inherit; text-wrap-mode: wrap; overflow-wrap: break-word; line-height: 19.2px;"><p style="box-sizing: inherit; margin-right: 0px; margin-left: 0px; padding: 0px; list-style: none; white-space-collapse: collapse; text-size-adjust: none; color: rgb(127, 127, 127); font-family: Golfzon, "Noto Sans Korean", nanumGothic, Dotum, sans-serif; font-size: 14px; letter-spacing: -1px;"><br style="box-sizing: inherit;"></p><p style="box-sizing: inherit; margin-right: 0px; margin-left: 0px; padding: 0px; list-style: none; font-family: NotoR; white-space-collapse: collapse; font-size: 16px;"><span style="box-sizing: border-box; font-family: Pretendard, "Malgun Gothic", 맑은고딕, 돋움, Dotum, sans-serif; font-size: 18px; letter-spacing: -0.25px;"></span></p><p style="box-sizing: inherit; margin-right: 0px; margin-left: 0px; padding: 0px; list-style: none; white-space-collapse: collapse; text-size-adjust: none; color: rgb(127, 127, 127); font-family: Golfzon, "Noto Sans Korean", nanumGothic, Dotum, sans-serif; font-size: 14px; letter-spacing: -1px;"><span style="box-sizing: inherit; color: rgb(49, 49, 49); font-family: 한양중고딕; font-size: 13pt; letter-spacing: -1.46667px; text-indent: -52.4px;">* 자세한 사항은 원문링크를 참고하시기 바랍니다.</span></p></pre>
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