Anti-Cancer Composition for Oral Administration Comprising Pegylated Betulin Derivatives SphereCancer Summary - PEG is a linear or branched polyether type refers to a polymer, economically manufactured by basic polymerization of ethylene oxide. - PEG have unique physical and chemical properties. for examples, It is water as well as oil soluble and easy to complex with metals. - PEG technoloy for commercialization is needed efforts for a long time because products is dfficult to purify, analyze and synthesize intermediates. Remarkable In contrast to the cytotoxicity of betulinic acid against a variety of cancer types, normal cells and tissue are relatively resistant to betulinic acid, pointing to a therapeutic window. However, the poor water solubility of this compound hampers an effective in vivo cancer study. We prepared new PEG(Poly etylene glycol) derivatives of betulinic acid with higher water solubilities and bioavalability. Our PEG technoloy applied for active substances such as betulinic acid. as a result, we can get new lead compounds with excellent oral efficacy. Contact Point Contact Point - Company, Name in Charge, Phone, Fax, Email Company HTTC Name in Charge Kim Dae Hyon Phone 82 +82-881-2842 Fax Email technomart@khidi.or.kr List